Organonitrogen Compounds
Medchemexpress LLC Hydroxylamine hydrochloride | 5470-11-1 | MFCD00051089 | 99.9% | 69.49 g/mol | ClH4NO | 1g
Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms such as ammonium oxidizing bacteria (AOB) ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox) Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity[1][2]
eMolecules 6638-79-5 | N,O-Dimethylhydroxylamine Hydrochloride | Accela ChemBio (ASD) | MFCD00012485 | 97.540 | C2H8ClNO | 98.000 | Cl.CNOC | 25g | 444744114
N,O-Dimethylhydroxylamine Hydrochloride | Accela ChemBio (ASD) | 6638-79-5 | MFCD00012485 | 97.540 | C2H8ClNO | 98.000 | Cl.CNOC | 25g | 444744114
Apexbio Technology LLC Amlodipine Besylate 111470-99-6 10mM (in 1mL DMSO)
Amlodipine Besylate (CAS 111470-99-6) is a long-acting calcium channel blocker that reduces blood pressure primarily through inhibition of calcium ion influx via voltage-gated calcium channels Calcium channel modulation influences critical cellular signaling pathways In cortical neurons exposed to oxidative stress Amlodipine Besylate ( 5 M) preserves cellular viability by reducing oxidative damage enhancing pro-survival signals and suppressing apoptotic pathways It has also demonstrated proliferative effects on human epidermoid carcinoma (A431) cells Furthermore clinical studies indicate that Amlodipine Besylate decreases peripheral vascular resistance and myocardial oxygen demand in angina patients and effectively lowers arterial pressure in hypertensive feline models
Medchemexpress LLC To-1187 TFA | 98.4% | 795.72 | 100 MG
TO-1187 TFA is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It functions by promoting the ubiquitination and degradation of HDAC6 and can be used in the study of hematological malignancies and solid tumors. The compound is described as being composed of an HDAC6 ligand (HY-173386), a CRBN ligase ligand (HY-41547), and a linker (HY-140212).
- Selective HDAC6 PROTAC degrader (DC50: 5.81 nM).
- Promotes the ubiquitination and degradation of HDAC6.
- Applicable in the study of hematological malignancies and solid tumors.
Medchemexpress LLC (S)-Nimodipine | 77940-93-3 | 99.9% | 418.44 | 1 MG
(S)-Nimodipine is an enantiomer of Nimodipine, a light-sensitive dihydropyridine calcium antagonist. This orally active and well-tolerated compound is utilized in the research of cerebrovascular disorders.
- Enantiomer of Nimodipine
- Orally active
- Dihydropyridine calcium antagonist
- Target: Calcium channel
- Pathway: Membrane transporter/ion channel; neuronal signaling
- Appearance: White to off-white solid
- Purity: 99.9%
- Molecular formula: C21H26N2O7
Accela Chembio Inc Isopropyl 3-aminocrotonate | 100g | 14205-46-0 | MFCD00134272 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4
Isopropyl 3-aminocrotonate | 100g | 14205-46-0 | MFCD00134272 | 97+% | Shelf Life: 1260 Days | Light Sensitive/+4
Medchemexpress LLC CDK2-IN-4 | 1316652-41-1 | 99.3% | 326.37 g/mol | C16H14N4O2S | 5 MG
NCC-149 is a selective histone deacetylase 8 (HDAC8) inhibitor used in cell biology research, including studies of neural differentiation. The product is provided with supporting documentation for purity, handling, and storage, and is available both as a solid and as a DMSO solution.
- Selective HDAC8 inhibitor for neural differentiation studies.
- Documented purity approximately 99.3% based on certificate of analysis.
- Available as a solid and as a 10 mM solution in DMSO.
- Datasheet, certificate of analysis, and safety data sheet provided for quality and safety information.
- Storage recommendations included for powdered material and solutions.
Selleck Chemical LLC Nimodipine S1747-1g
Nimodipine (BAY E 9736) is a dihydropyridine calcium channel blocker and an autophagy inhibitor used in the treatment of high blood pressure
eMolecules 14205-39-1 | Methyl 3-aminocrotonate | Chem-Impex115.132 | C5H9NO2 | 98.000 | COC(=O)C=C(C)N | 25g | 386901549
Methyl 3-aminocrotonate | Chem-Impex | 14205-39-1115.132 | C5H9NO2 | 98.000 | COC(=O)C=C(C)N | 25g | 386901549
Medchemexpress LLC TO-1187 (TFA) | 98.4% | 795.72 | C36H36F3N9O9 | 10 MG
TO-1187 TFA is a selective PROTAC degrader that targets HDAC6 and recruits cereblon to promote ubiquitination and proteasomal degradation of HDAC6. Supplied as a trifluoroacetic acid salt in solid form, it is intended as a research tool for cellular and preclinical studies investigating HDAC6 biology and PROTAC-mediated target removal.
- Selective HDAC6 degrader with DC50 of 5.81 nM.
- Engages cereblon to induce ubiquitination and proteasomal degradation.
- High chemical purity (98.4%) suitable for biochemical and cellular assays.
- Provided as a solid TFA salt for stable handling and storage.
- Includes analytical documentation such as COA, H NMR, LCMS, and RP-HPLC.
- Storage recommended at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).